The egitema study reported the clinical case of a patient with eib who, after tuberculosis treatment, evolved with adrenal insufficiency. Red indurated papule appears 1 3 weeks after penetrating injury. Eritema induratum bazin pdf we describe two cases of erythema induratum of bazin eib, a cutaneous form of tb. Erythema induratum of bazin victoria sharon md, heidi goodarzi md, cindy j chambers mph, maxwell a fung md, april w armstrong md dermatology online journal 16 4. Degitz k 1993 successful treatment of erythema induratum of bazin following rapid detection of mycobacterial dna by polymerase chain reaction. Erythema induratum of bazin eib is a tuberculid showing lobular panniculitis. Diagnosis and treatment of erythema induratum bazin michael feiwel and dowling d.
Erythema induratum of bazin is a rare disease, characterized by the appearance of cutaneous erythema tous nodules, sometimes painful with frequent evolution to ulceration. This infectionrelated cutaneous condition article is a stub. Erythema induratum of bazin tuberculosis in disguise. It is traditionally considered to be the tuberculous counterpart of nodular vasculitis, but is now known to occur without tuberculous precedent. It is considered to be a hypersensitivity reaction to m. We present a case of a 43yearold lady with recurrent crops of nodules on legs. Erythema induratum of bazin is a chronic, nodular eruption that usually occurs on the lower legs of young women.
The egitema study reported the clinical case of a patient with eib who, after tuberculosis treatment, evolved with. Erythema induratum is characterized by painful, erythematous, sometimes ulcerating nodules on the lower. Jun 18, 2019 eritema induratum bazin pdf we describe two cases of erythema induratum of bazin eib, a cutaneous form of tb. In 1945, montgomery et al, while fully acknowledging the existence of tuberculosisassociated erythema induratum, coined the term nodular vasculitis to describe chronic inflammatory nodules of the legs that s. Primary tuberculosis of the nasopharynx with erythema induratum of bazin. The existence of cutaneous nodules makes it necessary to perform a differential diagnosis between different clinical entities. Diagnosis and treatment of erythema induratum bazin. It occurs mainly in women, but it is very rare now. Successful treatment of erythema induratum of bazin following. However, it has been the practice for the last 50 years or so to recognize two variants one of presumptive tuberculous origin erythema induratum, bazintype and the other of nontuberculous origin, known as nodular vasculitis or erythema induratum, whitfieldtype. Erythema induratum of bazin associated with addisons disease.
Successful treatment of erythema induratum of bazin. Nodulare vaskulitis altmeyers enzyklopadie fachbereich. Erythema induratum of bazin eibalso known as bazin disease, tuberculosum, tuberculosis cutis indurativa and nodose tuberculid, is a chronic, indudado eruption that usually occurs on the lower legs of young women. A type of panniculitis characterized histologically by the presence of granulomas, vasculitis, and necrosis. Cases had no signs of active tb, but had a positive interferon. It has been regarded as a manifestation of tuberculin hypersensitivity, a type of. This report documents the cases of two patients with ulcerating leg nodules. Erythema induratum an overview sciencedirect topics.
Erythema induratum of bazin type associated with tb. Erythema induratum of bazin in a patient with endometrial tuberculosis. Treatment with a standard fourdrug antituberculous regimen resulted in radiographic and clinical improvement. Erythema induratum of bazin is a rare entity, the cause and treatment of which are topics of continuing controversy.
It is considered to be a hypersensitivity response to mycobacterium tuberculosis. Eritema e um sinal clinico presente em varias patologias e caracterizado por um rubor da pele ocasionado pela vasodilatacao capilar. Erythema induratum is a panniculitis on the calves. A purified protein derivative and quantiferon test were positive, favoring the diagnosis of erythema induratum of bazin. Erythema induratum of bazin eib is considered to be a tuberculid reaction and consists of recurrent painful nodules. Changes in cortisol metabolism following rifampicin therapy. Apr 15, 2010 a biopsy revealed changes consistent with nodular vasculitis. Review of eleven cases of erythema induratum at a second level hospital. Nov 15, 2019 in 1861, bazin gave the name erythema induratum to a nodular eruption that occurred on the lower legs of young women with tuberculosis. Nov 24, 2014 erythema induratum and nodular vasculitis had been seen as the same disease for many years but nodular vasculitis is now considered to be a multifactorial syndrome of lobular panniculitis in which tuberculosis may or may not be one of the various aetiologies. When weather is cold, ankle is cold, blue and often tender.
In 1861, bazin gave the name erythema induratum to a nodular eruption that occurred on the lower legs of young women with tuberculosis. Historically, when it has occurred, it has often been concomitant with cutaneous tuberculosis, and it was formerly thought to be always a reaction to the tuberculum bacillus. Dermis erythema induratum bazin information on the diagnosis. Erythema induratum is characterized by painful, erythematous, sometimes ulcerating nodules on. This website is intended for pathologists and laboratory personnel. Computed tomography showed bilateral enlargement of the adrenal glands, with preserved outlines. Links to pubmed are also available for selected references. An 81yearold woman with a history of renal cell carcinoma and years of slowly, progressively enlarging pulmonary nodules of uncertain etiology presented with. Get a printable copy pdf file of the complete article 905k, or click on a page image below to browse page by page. A biopsy revealed changes consistent with nodular vasculitis.
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